SCHEMBL7861888

SCHEMBL7861888

c1ccc(CCc2ccc(Cc3ccccc3)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.75
MAOB P27338 3/20 0.62
MAOA P21397 2/20 0.62
ALDH1A1 P00352 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
CASP1 P29466 1/20 0.55
HSD17B10 Q99714 1/20 0.55
LTA4H P09960 2/20 0.54
FFAR1 O14842 1/20 0.54
TDP1 Q9NUW8 2/20 0.52
TAAR1 Q96RJ0 2/20 0.52
HTR2A P28223 2/20 0.52
CYP2A6 P11509 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
ATM Q13315 1/20 0.52
IDH1 O75874 1/20 0.52
PLA2G10 O15496 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55138 0.90 MAOB (0.72) CALM1MAOBMAOAALDH1A1HPGD
SCHEMBL8094422 0.90 CALM1 (0.92) CALM1ALDH1A1LTA4HTDP1LOXL2
SCHEMBL12506236 0.90 MAOB (0.72) CALM1MAOBMAOAALDH1A1HPGD
SCHEMBL972712 0.90 CALM1 (0.92) CALM1ALDH1A1LTA4HTDP1LOXL2
SCHEMBL10599557 0.88 CALM1 (0.67) CALM1MAOBMAOALTA4HHTR2A
SCHEMBL10598930 0.88 CALM1 (0.67) CALM1MAOBMAOAALOX15LTA4H
Hydrochloric Acid SCHEMBL27978245 0.87 CALM1 (0.86) CALM1MAOBMAOAALDH1A1LTA4H
SCHEMBL62125 0.87 ALDH1A1 (0.69) CALM1MAOBMAOAALDH1A1HPGD
SCHEMBL9741303 0.87 ALDH1A1 (0.69) CALM1MAOBMAOAALDH1A1HPGD
Diphenylmethane SCHEMBL14763944 0.87 CALM1 (1.00) CALM1MAOBALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0953194-B1 ELECTRIC CABLE NKT CABLES AS (DK) 2001-05-16 EP claimed
EP-0953194-A1 ELECTRIC CABLE NKT Cables A/S (DK) 1999-11-03 EP claimed
WO-1998032137-A1 ELECTRIC CABLE NKT CABLES A/S (DK) 1998-07-23 WO claimed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US claimed
JP-61081492-A None JP disclosed
EP-0953194-B1 ELECTRIC CABLE NKT CABLES AS (DK) 2001-05-16 EP disclosed
EP-0953194-A1 ELECTRIC CABLE NKT Cables A/S (DK) 1999-11-03 EP disclosed
WO-1998032137-A1 ELECTRIC CABLE NKT CABLES A/S (DK) 1998-07-23 WO disclosed
EP-0176366-B1 IMPREGNATED CAPACITOR NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-25 EP disclosed
US-4631632-A METALLIZED POLYPROPYLENE FILM IMPREGNATED WITH DIELECTRIC HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-12-23 US disclosed
JP-S6181492-A LUBRICANT OIL FOR TRANSMISSION NIPPON STEEL CHEM CO LTD 1986-04-25 JP disclosed
EP-0176366-A2 Impregnated capacitor NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-04-02 EP disclosed
EP-0171081-A2 Oil-filled capacitor Nippon Petrochemicals Company, Limited (JP) 1986-02-12 EP disclosed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed
JP-S06181492-A 0001-01-01 JP disclosed