Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PER2 | O15055 | 3/20 | 0.30 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.30 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855282 | 0.84 | CYP3A4 (0.36) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7855114 | 0.77 | ALDH1A1 (0.34) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7861851 | 0.77 | MAPT (0.36) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7855084 | 0.77 | ALDH1A1 (0.52) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7861900 | 0.77 | CYP3A4 (0.38) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7862058 | 0.77 | ALDH1A1 (0.52) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7862042 | 0.76 | MAPT (0.37) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7862016 | 0.76 | MAPT (0.37) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL7810757 | 0.69 | SMN1; SMN2 (0.42) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL6944894 | 0.68 | CYP3A4 (0.74) | LMNAHSP90AA1CYP3A4CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120397-A2 | Process for preparing triazole derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | disclosed |
| US-6046354-A | CHEMICAL INTERMEDIATES, E.G. 2-ARYL-1,3-DIACYLOXY-2-PROPANOL, FOR DRUGS AND FUNGICIDES,E.G. (R)-2-(2,4-DIFLUOROPHENYL)-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPANE-1,2-DIOL, | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-04-04 | — | — | US | disclosed |
| US-5840553-A | OPTICALLY ACTIVE 2-ARYL-3-ACYLOXY-1,2,-PROPANE DIOL USING A MICROORGANISM OR ENZYME DERIVED FROM PORCINE PANCREAS; VIA STEREOSPECIFIC HYDROLYSIS OF A 2-ARYL-1,3-DIACYLOXY-2-PROPANOL; SYNTHETIC CHEMICAL INTERMEDIATES, FUNGICIDES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5654472-A | OPTICALLY PURE 2-ARYL-3-ACYLOXY-1,2-PROPANEDIOL COMPOUNDS; CHEMICAL INTERMEDIATES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0704419-A1 | PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |