Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727 | 0.96 | CYP1A2 (0.44) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL26519 | 0.91 | CYP1A2 (0.42) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL7865257 | 0.78 | HSD11B1 (0.56) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL14459065 | 0.78 | HSD11B1 (0.56) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL5443318 | 0.75 | CYP1A2 (0.39) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL5441518 | 0.75 | CYP1A2 (0.39) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL7403691 | 0.75 | CYP1A2 (0.39) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL5441916 | 0.75 | CYP1A2 (0.39) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL5456118 | 0.75 | CYP1A2 (0.39) | ALDH1A1CYP1A2USP2LMNATSHR | |
| SCHEMBL5441921 | 0.75 | CYP1A2 (0.39) | ALDH1A1CYP1A2USP2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888285-B1 | NOVEL BRIDGED CYCLIC AMINO ACIDS AS PHARMACEUTICAL AGENTS | WARNER LAMBERT CO (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6020370-A | ANTIEPILEPIC AGENT, BRAIN DISORDERS, NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS, ANALGESICS | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |