Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770299 | 0.91 | HPGD (0.56) | HPGDLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9324567 | 0.85 | THRA (0.58) | HPGDLMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL1017480 | 0.83 | HPGD (0.72) | HPGDLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9514803 | 0.83 | HPGD (0.69) | HPGDLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL29371530 | 0.82 | SMN1; SMN2 (0.48) | HPGDLMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9490752 | 0.81 | HPGD (0.70) | HPGDLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL457811 | 0.81 | HPGD (0.67) | HPGDLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL2026762 | 0.81 | HPGD (0.57) | HPGDLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL31299076 | 0.80 | HPGD (0.53) | HPGDLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9490759 | 0.80 | HPGD (0.65) | HPGDLMNASMN1; SMN2HTTPANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024235073-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 浙江海正药业股份有限公司 | 2024-11-21 | — | — | WO | disclosed |
| EP-3962479-A1 | KCNT1 INHIBITORS AND METHODS OF USE | Praxis Precision Medicines, Inc. (US) | 2022-03-09 | — | — | EP | disclosed |
| EP-1086063-A4 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | ADVANCED MEDICINE INC (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-1086063-A1 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | Advanced Medicine, Inc. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064050-A9 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | ADVANCED MEDICINE INC (US) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999064050-A1 | NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |