SCHEMBL9324567

SCHEMBL9324567

CCCCS(=O)(=O)Nc1ccc(C(N)=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.58
HPGD P15428 5/20 0.54
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 4/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
AR P10275 1/20 0.50
AURKA O14965 1/20 0.47
KDR P35968 1/20 0.47
AURKB Q96GD4 1/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPK1 P28482 1/20 0.47
NAMPT P43490 1/20 0.46
MRGPRX1 Q96LB2 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KIT P10721 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8231736 0.86 THRA (0.59) THRAHPGDLMNASMN1; SMN2AR
SCHEMBL7861945 0.85 HPGD (0.67) HPGDLMNASMN1; SMN2NPC1RAB9A
SCHEMBL9491401 0.84 THRA (0.58) THRAHPGDLMNASMN1; SMN2AR
SCHEMBL9324564 0.84 THRA (0.58) THRAHPGDLMNASMN1; SMN2AR
SCHEMBL6090805 0.83 HPGD (0.74) THRAHPGDLMNASMN1; SMN2NPC1
SCHEMBL29371530 0.82 SMN1; SMN2 (0.48) THRAHPGDLMNASMN1; SMN2ALDH1A1
SCHEMBL7404753 0.82 THRA (0.62) THRAHPGDLMNASMN1; SMN2AR
SCHEMBL11709119 0.82 HPGD (0.75) THRAHPGDLMNASMN1; SMN2RAB9A
SCHEMBL9425268 0.82 THRA (0.62) THRAHPGDLMNASMN1; SMN2AR
SCHEMBL16051464 0.81 THRA (0.65) THRAHPGDLMNASMN1; SMN2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321190-B1 Silver halide color photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1994-02-09 EP disclosed
US-5162293-A Cyan Dyes KONICA CORPORATION (JP) 1992-11-10 US disclosed
US-5017467-A Colorfastness, reproducibility KONICA CORPORATION (JP) 1991-05-21 US disclosed
US-4996139-A Silver halide photographic light-sensitive material containing novel cyan coupler KONICA CORPORATION (JP) 1991-02-26 US disclosed
US-4994362-A Storage stability KONICA CORPORATION (JP) 1991-02-19 US disclosed
US-4921783-A Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1990-05-01 US disclosed
EP-0320778-A2 Silver halide photograhic lightsensitive material KONICA CORPORATION (JP) 1989-06-21 EP disclosed
EP-0304856-A2 Silver halide color photograhic light-sensitive material KONICA CORPORATION (JP) 1989-03-01 EP disclosed