Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974321 | 0.83 | EPHX2 (0.70) | KDREPHX2KMT2ASMN1; SMN2GAA | |
| SCHEMBL11926736 | 0.82 | KDM4E (0.65) | KDREPHX2SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5487329 | 0.81 | NR3C1 (0.62) | KDREPHX2NR3C1SMN1; SMN2GAA | |
| SCHEMBL19799087 | 0.80 | KDR (0.56) | KDREPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL5998386 | 0.79 | JAK2 (0.59) | KDRBRAF | |
| SCHEMBL31174709 | 0.77 | EPHX2 (0.79) | KDREPHX2SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1801810 | 0.77 | CD274 (0.62) | KDREPHX2SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7874113 | 0.76 | SMN1; SMN2 (0.65) | KDRSMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL16178361 | 0.76 | EPHX2 (0.57) | KDREPHX2KMT2ASMN1; SMN2GAA | |
| SCHEMBL4269280 | 0.76 | EPHX2 (0.86) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |