Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860539 | 0.91 | MEN1 (0.46) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL7861761 | 0.91 | MEN1 (0.49) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL7860490 | 0.89 | ATM (0.45) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL13039822 | 0.78 | CTSB (0.52) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL3729761 | 0.78 | CTSB (0.52) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL22685692 | 0.78 | CTSB (0.58) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL2150881 | 0.78 | CTSB (0.58) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL2150884 | 0.78 | CTSB (0.58) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL2221511 | 0.76 | CTSB (0.56) | MEN1KMT2ACASP3CYP3A4CYP2D6 | |
| SCHEMBL3739447 | 0.76 | MEN1 (0.45) | MEN1KMT2ACASP3CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |