Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862192 | 0.91 | MEN1 (0.46) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL7860539 | 0.91 | MEN1 (0.46) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL7860490 | 0.89 | ATM (0.45) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL3727297 | 0.80 | CA2 (0.53) | MEN1KMT2ACASP3CTSLCTSB | |
| SCHEMBL7860507 | 0.77 | CA2 (0.52) | MEN1KMT2ACASP1CTSLCTSB | |
| SCHEMBL3740424 | 0.77 | NR4A1 (0.51) | MEN1KMT2ACTSLCTSBCTSK | |
| SCHEMBL3736355 | 0.75 | CTSB (0.57) | MEN1KMT2ACASP3CASP1CASP7 | |
| SCHEMBL3728204 | 0.75 | CA2 (0.54) | MEN1KMT2ACTSLCTSBCTSK | |
| SCHEMBL3725788 | 0.74 | CTSB (0.56) | MEN1KMT2ACASP3CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL18954406 | 0.73 | CTSB (0.55) | MEN1KMT2ACASP3CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |