Sugi Predict

Sugi Predict / Compounds / SCHEMBL7862219

SCHEMBL7862219

SCHEMBL7862219

O=C(Cl)c1cc2ccccc2oc1=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 8/20 0.72
▸ CA12 O43570 2/20 0.72
▸ CA9 Q16790 2/20 0.72
▸ CA1 P00915 1/20 0.72
▸ CA3 P07451 1/20 0.72
▸ TSHR P16473 1/20 0.72
▸ CA4 P22748 1/20 0.72
▸ CA6 P23280 1/20 0.72
▸ CA5A P35218 1/20 0.72
▸ CA7 P43166 1/20 0.72
▸ GPR35 Q9HC97 1/20 0.72
▸ CA14 Q9ULX7 1/20 0.72
▸ CA5B Q9Y2D0 1/20 0.72
▸ KDM4E B2RXH2 4/20 0.70
▸ CYP1A2 P05177 2/20 0.70
▸ NT5E P21589 1/20 0.70
▸ ALDH1A1 P00352 3/20 0.64
▸ HPGD P15428 2/20 0.64
▸ MAOA P21397 4/20 0.63
▸ LMNA P02545 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16339253 0.86 MAOB (0.72) MAOBCA12CA9CA1CA3
SCHEMBL279860 0.85 MAOB (0.77) MAOBCA12CA9CA1CA3
SCHEMBL29539474 0.85 MAOB (0.77) MAOBCA12CA9CA1CA3
SCHEMBL34468463 0.85 MAOB (0.77) MAOBCA12CA9CA1CA3
Coumarin-3-Carboxylic Acid SCHEMBL93571 0.84 MAOB (1.00) MAOBCA12CA9CA1CA3
SCHEMBL31078224 0.84 MAOB (0.74) MAOBCA12CA9CA1CA3
Coumarin-3-Carboxylic Acid SCHEMBL29414591 0.84 MAOB (1.00) MAOBCA12CA9CA1CA3
SCHEMBL7701761 0.82 MAOB (0.72) MAOBCA12CA9CA1CA3
3-Acetylcoumarin SCHEMBL181862 0.82 MAOB (1.00) MAOBCA12CA9CA1CA3
Coumarin-3-Carboxylic Acid SCHEMBL31756872 0.82 MAOB (0.96) MAOBCA12CA9CA1CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505033-A Chitosan oligosaccharide derivative with antibacterial property as well as preparation method and application thereof 扬州工业职业技术学院 2025-02-25 — — CN claimed
CN-112175195-B Supramolecular polymer gel, preparation thereof and application of supramolecular polymer gel in fluorescent recognition of iron ions and fluorine ions 陇东学院 2022-02-11 — — CN claimed
CN-112175195-A Supramolecular polymer gel, preparation thereof and application of supramolecular polymer gel in fluorescent recognition of iron ions and fluorine ions 陇东学院 2021-01-05 — — CN claimed
CN-107698571-B Naphthalimide-coumarin DNA targeting double-intercalator, synthesis and application thereof 大连理工大学 2020-07-14 — — CN claimed
CN-119505033-A Chitosan oligosaccharide derivative with antibacterial property as well as preparation method and application thereof 扬州工业职业技术学院 2025-02-25 — — CN disclosed
WO-2023213728-A1 SUBSTITUTED ARYL ESTERS OF COUMARIN-3-CARBOXYLIC ACID AND THEIR USE AS HOST CELL PROTEASES INHIBITORS Université de Liège (BE) 2023-11-09 — — WO disclosed
CN-116655573-A Oxime ester compound and preparation method and application thereof 安庆师范大学 2023-08-29 — — CN disclosed
CN-112175195-B Supramolecular polymer gel, preparation thereof and application of supramolecular polymer gel in fluorescent recognition of iron ions and fluorine ions 陇东学院 2022-02-11 — — CN disclosed
CN-112175195-A Supramolecular polymer gel, preparation thereof and application of supramolecular polymer gel in fluorescent recognition of iron ions and fluorine ions 陇东学院 2021-01-05 — — CN disclosed
CN-107698571-B Naphthalimide-coumarin DNA targeting double-intercalator, synthesis and application thereof 大连理工大学 2020-07-14 — — CN disclosed
US-20180086707-A1 DISUBSTITUTED PIPERIDINE DERIVATIVES AS BUTYRYLCHOLINESTERASE INHIBITORS FOR USE IN THE TREATMENT OF ALZHEIMER UNIVERZA V LJUBLJANI (SI) 2018-03-29 — — US disclosed
US-20180086707-A1 DISUBSTITUTED PIPERIDINE DERIVATIVES AS BUTYRYLCHOLINESTERASE INHIBITORS FOR USE IN THE TREATMENT OF ALZHEIMER UNIVERZA V LJUBLJANI (SI) 2018-03-29 — — US disclosed
US-4877783-A β-lactam antibacterial agents BEECHAM GROUP P.L.C. (GB) 1989-10-31 — — US disclosed
EP-0071395-B1 BETA-LACTAM ANTIBACTERIAL AGENTS BEECHAM GROUP PLC (GB) 1988-08-10 — — EP disclosed
US-4609652-A FORMAMIDYL DERIVATIVES OF AMINO ACID DERIVATIVE ANTIBIOTICS BEECHAM GROUP P.L.C. (GB) 1986-09-02 — — US disclosed
US-4539149-A β-Lactam antibacterial agents BEECHAM GROUP P.L.C. (GB) 1985-09-03 — — US disclosed
EP-0071395-A1 Beta-lactam antibacterial agents BEECHAM GROUP PLC (GB) 1983-02-09 — — EP disclosed
US-4285941-A ANTIBIOTICS EISAI CO., LTD. (JP) 1981-08-25 — — US disclosed
US-4240967-A BRIGHT COLORS WHICH ARE COLORFAST, DURABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-12-23 — — US disclosed
US-3937837-A SUBSTITUTED CHROMONE-3-CARBONITRILES, CARBOXAMIDES AND CARBOXYLIC ACIDS USEFUL FOR PREVENTING ASTHMATIC SYMPTOMS WARNER-LAMBERT COMPANY (US) 1976-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086707-A1 DISUBSTITUTED PIPERIDINE DERIVATIVES AS BUTYRYLCHOLINESTERASE INHIBITORS FOR USE IN THE TREATMENT OF ALZHEIMER BCHE, PSEN1, ACHE MAOB 31/4885CA12 3526/4885CA9 2083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.