⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168016 | 0.94 | HTR1D (0.57) | — | |
| SCHEMBL5680179 | 0.92 | HTR1D (0.56) | — | |
| SCHEMBL1626311 | 0.92 | HTR1D (0.56) | — | |
| SCHEMBL7756299 | 0.92 | HTR1D (0.56) | — | |
| SCHEMBL5675527 | 0.92 | HTR1D (0.56) | — | |
| SCHEMBL2845525 | 0.92 | HTR1D (0.56) | — | |
| Propane SCHEMBL9444503 | 0.92 | HTR1D (0.56) | — | |
| SCHEMBL15561019 | 0.92 | HTR1D (0.56) | — | |
| SCHEMBL1736375 | 0.92 | HTR1D (0.56) | — | |
| SCHEMBL107099 | 0.92 | HTR1D (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | claimed |
| WO-2023183394-A1 | ALPHA 1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | CURASEN THERAPEUTICS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20230062712-A1 | ANTI-ASGR1 ANTIBODY CONJUGATES AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11566015-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-11541126-B1 | Anti-ASGR1 antibody TLR8 agonist comprising conjugates and uses thereof | SILVERBACK THERAPEUTICS, INC. (US) | 2023-01-03 | — | — | US | disclosed |
| US-20220152215-A1 | Immunoconjugates Targeting CEA | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-05-19 | — | — | US | disclosed |
| CN-114096377-A | Flux, rosin-cored solder using flux, flux-coated solder using flux, and soldering method | 千住金属工业株式会社 | 2022-02-25 | — | — | CN | disclosed |
| US-20210238164-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2021-08-05 | — | — | US | disclosed |
| US-20210002254-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2021-01-07 | — | — | US | disclosed |
| US-20200216415-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2020-07-09 | — | — | US | disclosed |
| US-20150158970-A1 | LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (II) | ALZCHEM AG (DE) | 2015-06-11 | — | — | US | disclosed |
| US-20150158972-A1 | LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (I) | ALZCHEM AG (DE) | 2015-06-11 | — | — | US | disclosed |
| EP-2880072-A2 | LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (II) | AlzChem AG (DE) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014020072-A2 | LIQUID HARDENERS FOR HARDENING EPOXIDE RESINS (II) | ALZCHEM AG (DE) | 2014-02-06 | — | — | WO | disclosed |
| US-20080171769-A1 | Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders | CHEMBRIDGE CORPORATION | 2008-07-17 | — | — | US | disclosed |
| US-7301037-B2 | Charged compounds comprising a nucleic acid binding moiety and uses therefor | GENESOFT, INC. (US) | 2007-11-27 | — | — | US | disclosed |
| US-20070105135-A1 | Charged compounds comprising a nucleic acid binding moiety and uses therefor | GENESOFT PHARMACEUTICALS, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| EP-0331507-B1 | POLYVINYL CHLORIDE PLASTISOL COMPOSITION | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4977201-A | Blended with modified epoxy resin, blocked isocyanate, latent curing for resin as tackifier, automobile undercoatings | ASAHI DENKA KOGYO K.K. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0331507-A1 | Polyvinyl chloride plastisol composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1989-09-06 | — | — | EP | disclosed |