Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864481 | 0.76 | THRB (0.35) | THRBLMNA | |
| SCHEMBL9261817 | 0.75 | THRB (0.44) | THRBLMNA | |
| SCHEMBL6376304 | 0.73 | THRB (0.42) | THRBLMNA | |
| SCHEMBL7864497 | 0.71 | THRB (0.40) | THRBLMNA | |
| SCHEMBL703016 | 0.71 | THRB (0.40) | THRBLMNA | |
| SCHEMBL8988986 | 0.69 | THRB (0.38) | THRBLMNA | |
| SCHEMBL20464014 | 0.65 | THRB (0.35) | THRBLMNA | |
| SCHEMBL6786510 | 0.65 | THRB (0.35) | THRBLMNA | |
| SCHEMBL27639860 | 0.65 | THRB (0.47) | THRBLMNA | |
| SCHEMBL9083702 | 0.65 | LMNA (0.45) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709394-B1 | Steroids with a 17-spiromethylene lactone or lactol group | AKZO NOBEL NV (NL) | 2001-01-31 | — | — | EP | disclosed |
| US-5741786-A | PROGESTATIONAL ACTIVITY, USED AS CONTRACEPTIVES | AKZO NOBEL N.V. (NL) | 1998-04-21 | — | — | US | disclosed |
| EP-0709394-A2 | Steroids with a 17-spiromethylene lactone or lactol group | Akzo Nobel N.V. (NL) | 1996-05-01 | — | — | EP | disclosed |