Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558495 | 0.90 | HDAC4 (0.53) | KMT2AMEN1PGRHDAC4SRC | |
| SCHEMBL8145505 | 0.89 | HDAC4 (0.59) | KMT2AMEN1PGRHDAC4SRC | |
| SCHEMBL7558383 | 0.88 | HDAC4 (0.71) | KMT2AMEN1PGRHDAC4SRC | |
| SCHEMBL7860231 | 0.86 | MEN1 (0.47) | KMT2AMEN1PGRHDAC4ALDH1A1 | |
| SCHEMBL8144306 | 0.85 | HDAC4 (0.58) | KMT2AMEN1PGRHDAC4SRC | |
| SCHEMBL17816198 | 0.85 | MEN1 (0.71) | KMT2AMEN1PGRHDAC4SRC | |
| SCHEMBL7722435 | 0.84 | MEN1 (0.45) | KMT2AMEN1PGRHDAC4ALDH1A1 | |
| SCHEMBL5167153 | 0.84 | MEN1 (0.70) | KMT2AMEN1PGRHDAC4SRC | |
| SCHEMBL8136643 | 0.83 | MEN1 (0.44) | KMT2AMEN1PGRHDAC4ALDH1A1 | |
| SCHEMBL8146108 | 0.83 | ALDH1A1 (0.43) | KMT2AMEN1PGRHDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097139-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| US-6121287-A | Quinoline derivatives | ACTIVE BIOTECH AB (SE) | 2000-09-19 | — | — | US | disclosed |
| WO-2000003992-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |