Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605923 | 1.00 | MCL1 (0.43) | MCL1SLC22A12MEN1KMT2ATYK2 | |
| SCHEMBL9069065 | 0.88 | TRPV4 (0.41) | MCL1SLC22A12MEN1KMT2ATRPV4 | |
| SCHEMBL30130315 | 0.83 | MCL1 (0.42) | MCL1SLC22A12MEN1KMT2ATYK2 | |
| SCHEMBL28918924 | 0.83 | MCL1 (0.42) | MCL1SLC22A12MEN1KMT2ATYK2 | |
| SCHEMBL29183881 | 0.83 | MCL1 (0.42) | MCL1SLC22A12MEN1KMT2ATYK2 | |
| SCHEMBL1501184 | 0.81 | SLC22A12 (0.42) | SLC22A12MEN1KMT2ATRPV4CES1 | |
| SCHEMBL30586543 | 0.81 | SLC22A12 (0.42) | SLC22A12MEN1KMT2ATRPV4CES1 | |
| SCHEMBL8409880 | 0.79 | KDM4E (0.38) | SLC22A12MEN1KMT2ATRPV4P2RX7 | |
| SCHEMBL8409006 | 0.79 | MEN1 (0.42) | SLC22A12MEN1KMT2ATRPV4P2RX7 | |
| SCHEMBL28582493 | 0.79 | CA1 (0.44) | SLC22A12MEN1KMT2ATRPV4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865771-A | Synthesis method of 2, 3-dichloro benzotrifluoride | 上海泰初化工技术有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117820180-A | Sulfonyl trifluoro toluene compound | 上海泰初化工技术有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117820176-A | Sulfoxide-based benzotrifluoride compound | 上海泰初化工技术有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-115490622-A | Trifluoromethyl thiophenol compound | 上海泰初化工技术有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-117865771-A | Synthesis method of 2, 3-dichloro benzotrifluoride | 上海泰初化工技术有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117820176-A | Sulfoxide-based benzotrifluoride compound | 上海泰初化工技术有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117820180-A | Sulfonyl trifluoro toluene compound | 上海泰初化工技术有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117820180-A | Sulfonyl trifluoro toluene compound | 上海泰初化工技术有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-115703726-B | Trifluoromethyl phenyl sulfide compound | 上海泰初化工技术有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023192801-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20230303509-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. | 2023-09-28 | — | — | US | disclosed |
| US-20230303509-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. | 2023-09-28 | — | — | US | disclosed |
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-16 | — | — | US | disclosed |
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303509-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | CDK2, CCNK, CCNI | MCL1 338/4885SLC22A12 3802/4885MEN1 2859/4885 |
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | MCL1 2221/4885SLC22A12 919/4885MEN1 4850/4885 |
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | MCL1 2545/4885SLC22A12 4030/4885MEN1 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.