Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869432 | 1.00 | EGFR (0.52) | EGFRPPARAMEN1KMT2ANAMPT | |
| SCHEMBL9574710 | 0.92 | EGFR (0.49) | EGFRPPARAMEN1KMT2ANAMPT | |
| SCHEMBL7862718 | 0.92 | EGFR (0.49) | EGFRPPARAMEN1KMT2ANAMPT | |
| SCHEMBL7870523 | 0.92 | MEN1 (0.47) | PPARAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7874555 | 0.91 | MAPT (0.51) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7871575 | 0.91 | KMT2A (0.56) | PPARAMEN1KMT2AGAANPC1 | |
| SCHEMBL7862777 | 0.91 | EGFR (0.53) | EGFRPPARAMEN1KMT2AFLT1 | |
| SCHEMBL7874505 | 0.91 | EGFR (0.53) | EGFRPPARAMEN1KMT2AFLT1 | |
| SCHEMBL7874565 | 0.91 | PPARA (0.46) | EGFRPPARAMEN1KMT2ANAMPT | |
| SCHEMBL7870558 | 0.91 | PPARA (0.46) | EGFRPPARAMEN1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |