Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131352 | 0.93 | ALDH1A1 (0.52) | ALDH1A1ENPEPKMT2AALOX15BLM | |
| SCHEMBL29142541 | 0.91 | ALDH1A1 (0.55) | ALDH1A1ENPEPKMT2AALOX15BLM | |
| SCHEMBL18822637 | 0.88 | — | — | |
| SCHEMBL7770036 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL28987429 | 0.86 | KMT2A (0.48) | ALDH1A1ENPEPKMT2AALOX15BLM | |
| SCHEMBL13845456 | 0.84 | PAOX (0.43) | ALDH1A1ENPEPCA1CA2GABRP | |
| SCHEMBL1879462 | 0.84 | ENPEP (0.63) | ALDH1A1ENPEPKMT2AALOX15MEN1 | |
| SCHEMBL5334204 | 0.84 | ALDH1A1 (0.62) | ALDH1A1ENPEPKMT2AALOX15BLM | |
| Iodide SCHEMBL28846315 | 0.82 | ENPEP (0.61) | ALDH1A1ENPEPKMT2AALOX15MEN1 | |
| SCHEMBL7862923 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ENPEPCA1CA2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747381-B1 | CARBAPENEM DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5707987-A | BACTERICIDE ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0747381-A1 | CARBAPENEM DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |