Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095110 | 0.80 | ATM (0.49) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL6841180 | 0.80 | ATM (0.51) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL10554014 | 0.79 | CTSK (0.48) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL29576042 | 0.78 | CTSK (0.50) | CTSKCTSLCTSBCTSS | |
| SCHEMBL10583222 | 0.77 | CTSK (0.49) | CTSKCTSB | |
| SCHEMBL10684888 | 0.77 | CTSK (0.49) | CTSKCTSB | |
| SCHEMBL8087046 | 0.77 | KDM4C (0.54) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL1437776 | 0.76 | TDP1 (0.53) | LMNAKMT2ATDP1 | |
| SCHEMBL856196 | 0.76 | CTSK (0.61) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL241564 | 0.76 | CTSK (0.61) | ATMCTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076663-A1 | FUNCTIONALIZED ALKYL AND ALKENYL SIDE CHAIN DERIVATIVES OF GLYCINAMIDES AS FARNESYL TRANSFERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055725-A1 | FUNCTIONALIZED ALKYL AND ALKENYL SIDE CHAIN DERIVATIVES OF GLYCINAMIDES AS FARNESYL TRANSFERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-11-04 | — | — | WO | disclosed |