SCHEMBL7863311

SCHEMBL7863311

[NH]c1ccc([NH])c(S(=O)(=O)O)c1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.33
TTR P02766 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 2/20 0.31
HPGD P15428 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
PGAM1 P18669 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10799138 0.82 TTR (0.31) TTRTSHRSMN1; SMN2LMNAHPGD
SCHEMBL342050 0.80 ALDH1A1 (0.44) TSHRSMN1; SMN2LMNAHPGDHSD17B10
SCHEMBL8020884 0.80 HSD17B10 (0.49) LMNAHPGDHIF1AHSD17B10PGAM1
SCHEMBL156325 0.78 POLB (0.43) MYCTSHRSMN1; SMN2LMNAHPGD
SCHEMBL157885 0.78 ALDH1A1 (0.39) MYCTSHRHIF1AHSD17B10
SCHEMBL8379021 0.78 MCL1 (0.38) TSHRHPGD
SCHEMBL1485931 0.78 CTDSP1 (0.42) TTRTSHRHPGDHSD17B10RAPGEF4
SCHEMBL1485975 0.78 RAPGEF4 (0.51) TTRTSHRHPGDHSD17B10RAPGEF4
SCHEMBL1805062 0.78 ALDH1A1 (0.34) TSHRSMN1; SMN2HPGDHSD17B10
SCHEMBL157769 0.78 FABP3 (0.43) LMNAHPGDHIF1AHSD17B10PGAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4634448-A CATIONIC TRIAZINE DYES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-01-06 US claimed
US-6300306-B1 TREATING HARD SURFACES, POLYOXYALKYLENE UNITS AND SULFONATEDPOLYAMIDES AND SULFONATED POLYFUNCTIONAL UNITS AND BINDING GROUPS WITH ESTER RHODIA CHIMIE (FR) 2001-10-09 US disclosed
US-4634448-A CATIONIC TRIAZINE DYES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-01-06 US disclosed
US-4453945-A Process for dyeing cellulose fibers of its union fibers with reactive triazinyl dye quaternized with nicotinic acid NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1984-06-12 US disclosed