Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38141 | 0.82 | ERCC5 (0.58) | GSK3BPTPN1ALDH1A1ERCC5FEN1 | |
| SCHEMBL29621373 | 0.82 | ERCC5 (0.58) | GSK3BPTPN1ALDH1A1ERCC5FEN1 | |
| Bromide SCHEMBL235266 | 0.81 | ERCC5 (0.56) | GSK3BPTPN1ALDH1A1ERCC5FEN1 | |
| SCHEMBL374630 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ERCC5FEN1CES2CES1 | |
| SCHEMBL33952 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ERCC5FEN1CES2CES1 | |
| SCHEMBL9409754 | 0.76 | PTPN1 (0.65) | GSK3BPTPN1ALDH1A1CES1SMN1; SMN2 | |
| SCHEMBL17376015 | 0.75 | ERCC5 (0.56) | GSK3BPTPN1ALDH1A1ERCC5FEN1 | |
| SCHEMBL28317790 | 0.74 | ALDH1A1 (0.54) | ALDH1A1ERCC5FEN1CES2CES1 | |
| SCHEMBL31519376 | 0.73 | ALDH1A1 (0.64) | GSK3BPTPN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1893853 | 0.73 | ALDH1A1 (0.64) | GSK3BPTPN1ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300321-B1 | LIPOPOLYAMINES | AVENTIS PHARMA S.A. (FR) | 2001-10-09 | — | — | US | disclosed |