Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30447581 | 0.87 | CCR1 (0.50) | PDE10ACYP2A6CCR1CCR5CCR8 | |
| SCHEMBL14224575 | 0.80 | CCR1 (0.65) | CYP2A6CCR1CCR5CCR8MEN1 | |
| SCHEMBL30447562 | 0.80 | CCR1 (0.42) | PDE10ACYP2A6CCR1CCR5CCR8 | |
| SCHEMBL5532401 | 0.77 | DHODH (0.49) | PDE10ADHODHMEN1KMT2ALDHA | |
| SCHEMBL645855 | 0.76 | KDM4E (0.49) | CCR1CCR5CCR8DHODHKMT2A | |
| SCHEMBL30447796 | 0.73 | CCR1 (0.47) | PDE10ACYP2A6CCR1CCR5CCR8 | |
| SCHEMBL3235044 | 0.72 | CCR1 (0.74) | CYP2A6CCR1CCR5CCR8MEN1 | |
| SCHEMBL2789829 | 0.72 | ASIC3 (0.52) | KDM4CKDM4AEGFRSMOCNR1 | |
| SCHEMBL7853202 | 0.71 | CCR1 (0.61) | CYP2A6CCR1CCR5CCR8KMO | |
| SCHEMBL19009238 | 0.70 | CYP2A6 (0.61) | PDE10ACYP2A6CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010018194-A1 | Luminescence assays | LJL BIOSYSTEMS, INC. | 2001-08-30 | — | — | US | disclosed |
| WO-2000023785-A2 | IMPROVEMENTS IN LUMINESCENCE ASSAYS | LJL BIOSYSTEMS, INC. (US) | 2000-04-27 | — | — | WO | disclosed |