SCHEMBL7863711

SCHEMBL7863711

Fc1[c]nc(C(F)(F)F)nc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5674943 0.69
SCHEMBL1149495 0.66
SCHEMBL5673681 0.62
SCHEMBL10361925 0.62
SCHEMBL790055 0.60
SCHEMBL855855 0.60 GAA (0.45)
SCHEMBL175478 0.59 ALDH1A1 (0.33)
SCHEMBL5673702 0.59
SCHEMBL17835440 0.59
SCHEMBL789989 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0773264-B1 Process for the preparation of triphenodioxazine dyes amidated on both sides and triphenodioxazine dyes DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-10-10 EP disclosed
EP-0641838-B1 Reactive dye-stuffs on basis of a substituted barbituric acid BAYER AG (DE) 1999-11-10 EP disclosed
US-5944854-A LEUCO DYES DYSTAR TEXTILFARBEN GMBH & CO. (DE) 1999-08-31 US disclosed
EP-0677557-B1 Dyes and the use thereof in inks for ink jet printing process BAYER AG (DE) 1999-01-13 EP disclosed
EP-0657509-B1 Polymeric dyestuffs and their use in inks for ink jet printing process BAYER AG (DE) 1998-10-21 EP disclosed
US-5744589-A FOR DYEING OR PRINTING SUBSTRATES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
US-5696258-A REDUCING TO LEUCO FORM; REOXIDATION DYSTAR TEXTILFARBEN GMBH (DE) 1997-12-09 US disclosed
EP-0542079-B1 Process for continuously reacting halogenopyrimidines with amines BAYER AG (DE) 1997-07-23 EP disclosed
EP-0773264-A1 Process for the preparation of triphenodioxazine dyes amidated on both sides and triphenodioxazine dyes DyStar Textilfarben GmbH &amp; Co. Deutschland KG (DE) 1997-05-14 EP disclosed
US-5625042-A DYEING OR PRINTING MATERIAL HYDROXY OR AMIDE GROUPS BY APPLYING DYES WITH DISAZO AND TRIAZINE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed
EP-0552629-A2 Reactive dyes BAYER AG (DE) 1993-07-28 EP disclosed
EP-0542079-A2 Process for continuously reacting halogenopyrimidines with amines BAYER AG (DE) 1993-05-19 EP disclosed
EP-0349848-B1 TRIPHENE DIOXAZINE DYES BAYER AG (DE) 1993-04-21 EP disclosed
EP-0525572-A2 Reactive dyes BAYER AG (DE) 1993-02-03 EP disclosed
EP-0338310-B1 REACTIVE DYES BAYER AG (DE) 1992-12-09 EP disclosed
EP-0321784-B1 FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS BAYER AG (DE) 1992-03-18 EP disclosed
US-5095102-A 6-SUBSTITUTED SULPHONYL-8-SULPHO-2-NAPHTHYL MONOAZO REACTIVE DYESTUFFS BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
US-5057609-A TRIPHENDIOXAZINE DYESTUFFS BAYER AKTIENGESELLSCHAFT (DE) 1991-10-15 US disclosed
EP-0443165-A1 Reactive dyes BAYER AG (DE) 1991-08-28 EP disclosed
EP-0432542-A2 Azo dyestuffs and intermediates for their preparation BAYER AG (DE) 1991-06-19 EP disclosed