Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 9/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | RHOC | P08134 | 1/20 | 0.45 |
| ▸ | RHOA | P61586 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368900 | 1.00 | L3MBTL1 (0.56) | L3MBTL1TACR1CA1CA2CA4 | |
| SCHEMBL7462348 | 0.93 | L3MBTL1 (0.54) | L3MBTL1TACR1CA1CA2CA4 | |
| SCHEMBL7823087 | 0.92 | TACR1 (0.66) | L3MBTL1TACR1CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL7865340 | 0.91 | RHOC (0.53) | L3MBTL1TACR1CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL5366316 | 0.91 | RHOC (0.53) | L3MBTL1TACR1CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL8475576 | 0.91 | TACR1 (0.64) | L3MBTL1TACR1CA1CA2CA4 | |
| SCHEMBL5365341 | 0.90 | CA1 (0.47) | L3MBTL1TACR1CA1CA2CA4 | |
| SCHEMBL5363052 | 0.90 | L3MBTL1 (0.51) | L3MBTL1TACR1CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL6132629 | 0.89 | CA1 (0.48) | L3MBTL1TACR1CA1CA2CA4 | |
| Hydrochloric Acid SCHEMBL5379462 | 0.89 | CA1 (0.51) | L3MBTL1TACR1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140924-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035915-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-22 | — | — | WO | disclosed |