SCHEMBL7864024

SCHEMBL7864024

Cc1ccc(C(C(=O)O)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GRM1 Q13255 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP1A2 P05177 1/20 0.44
SRC P12931 1/20 0.41
TP53 P04637 1/20 0.41
TRPA1 O75762 1/20 0.41
LMNA P02545 1/20 0.41
CHRM1 P11229 1/20 0.41
SLC6A2 P23975 1/20 0.41
ADRA1A P35348 1/20 0.41
HTR2B P41595 1/20 0.41
CACNA2D1 P54289 2/20 0.40
CACNA1B Q00975 2/20 0.40
CACNB1 Q02641 2/20 0.40
CACNA1G O43497 1/20 0.40
CACNA1C Q13936 1/20 0.40
CSNK2A1 P68400 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14677603 0.87 KMT2A (0.48) MEN1KMT2ATDP1SRCCACNA2D1
SCHEMBL21641668 0.83 KMT2A (0.36) MEN1KMT2AGRM1TDP1CYP1A2
SCHEMBL14360428 0.82 TRPA1 (0.59) MEN1KMT2ATDP1SRCTP53
SCHEMBL8960143 0.82 TRPA1 (0.44) MEN1KMT2AGRM1TDP1CYP1A2
SCHEMBL8960497 0.82 TRPA1 (0.44) MEN1KMT2AGRM1TDP1CYP1A2
SCHEMBL510476 0.80 MEN1 (0.42) MEN1KMT2AGRM1TDP1CYP1A2
SCHEMBL508943 0.80 TDP1 (0.42) MEN1KMT2AGRM1TDP1CYP1A2
SCHEMBL25894342 0.80 GRM1 (0.69) MEN1KMT2AGRM1TDP1CYP1A2
SCHEMBL9306566 0.80 KMT2A (0.48) MEN1KMT2ATDP1CACNA2D1CACNA1B
SCHEMBL14564048 0.78 CACNA2D1 (0.35) MEN1KMT2AGRM1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0488980-B1 Use of acid-base indicators for improving the wet hiding power of emulsion paints FINA RESEARCH (BE) 2001-07-18 EP claimed
EP-3880626-A2 INDICATOR FOR THE SANDING OF JOINT COMPOUNDS AND SPACKLES UNITED STATES GYPSUM COMPANY (US) 2021-09-22 EP disclosed
WO-2020102619-A2 INDICATOR FOR THE SANDING OF JOINT COMPOUNDS AND SPACKLES UNITED STATES GYPSUM COMPANY (US) 2020-05-22 WO disclosed
US-20200156999-A1 INDICATOR FOR THE SANDING OF JOINT COMPOUNDS AND SPACKLES UNITED STATES GYPSUM COMPANY 2020-05-21 US disclosed