SCHEMBL14360428

SCHEMBL14360428

Cc1ccc(C(C(=O)O)c2ccc(C)cc2O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.59
CHRM1 P11229 2/20 0.59
LMNA P02545 1/20 0.59
SLC6A2 P23975 1/20 0.59
ADRA1A P35348 1/20 0.59
HTR2B P41595 1/20 0.59
CSNK2A1 P68400 1/20 0.47
SRC P12931 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
IDO1 P14902 1/20 0.41
TDO2 P48775 1/20 0.41
TP53 P04637 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CXCR2 P25025 1/20 0.40
HPGD P15428 1/20 0.39
ADRB2 P07550 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL731207 0.91 TRPA1 (0.50) TRPA1CHRM1LMNASLC6A2ADRA1A
SCHEMBL28238190 0.82 TRPA1 (0.62) TRPA1CHRM1LMNASLC6A2ADRA1A
SCHEMBL11529752 0.82 LMNA (0.57) TRPA1CHRM1LMNASLC6A2ADRA1A
SCHEMBL7864024 0.82 MEN1 (0.44) TRPA1CHRM1LMNASLC6A2ADRA1A
SCHEMBL9294948 0.81 TRPA1 (0.55) TRPA1CHRM1LMNASLC6A2ADRA1A
Thymol SCHEMBL28080455 0.81 TRPA1 (0.78) TRPA1CHRM1LMNASLC6A2ADRA1A
SCHEMBL31413333 0.80 KMT2A (0.57) TRPA1CHRM1LMNASLC6A2ADRA1A
Thymol SCHEMBL28150359 0.80 TRPA1 (0.84) TRPA1CHRM1LMNASLC6A2ADRA1A
Thymol SCHEMBL29152602 0.79 LMNA (0.75) TRPA1CHRM1LMNASLC6A2ADRA1A
SCHEMBL19444459 0.79 TYR (0.48) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2726442-A1 MODIFIED AMINOCARBOXYLATES WITH IMPROVED SHELF LIFE AND PROCESSING PROPERTIES BASF SE (DE) 2014-05-07 EP disclosed
WO-2013000848-A1 MODIFIED AMINOCARBOXYLATES WITH IMPROVED SHELF LIFE AND PROCESSING PROPERTIES BASF SE (DE) 2013-01-03 WO disclosed