Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542402 | 0.95 | CYP3A4 (0.61) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL5176015 | 0.87 | FTO (0.51) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL11666220 | 0.87 | FTO (0.59) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL2314510 | 0.83 | FTO (0.60) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL385190 | 0.83 | HPGD (0.53) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL393726 | 0.82 | FTO (0.47) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL6685820 | 0.82 | FTO (0.53) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL4519856 | 0.80 | FTO (0.63) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL22110384 | 0.80 | FTO (0.56) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL7524436 | 0.80 | FTO (0.56) | FTOHPGDMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133697-A1 | METHOD FOR MODIFYING AND IDENTIFYING FUNCTIONAL SITES IN PROTEINS | Xerion Pharmaceuticals GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031544-A1 | METHOD FOR MODIFYING AND IDENTIFYING FUNCTIONAL SITES IN PROTEINS | XERION PHARMACEUTICALS GMBH (DE) | 2000-06-02 | — | — | WO | disclosed |