Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864064 | 0.87 | FTO (0.55) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL3831388 | 0.86 | CYP3A4 (0.55) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL7542402 | 0.85 | CYP3A4 (0.61) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL562151 | 0.82 | FTO (0.54) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL8203426 | 0.80 | MAPT (0.53) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL2314510 | 0.77 | FTO (0.60) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL6685820 | 0.76 | FTO (0.53) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL3164943 | 0.76 | CYP3A4 (0.87) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL11666220 | 0.76 | FTO (0.59) | FTOHPGDMAPTMEN1HTT | |
| SCHEMBL17079673 | 0.76 | FTO (0.55) | FTOHPGDMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4379062-A1 | BIOSYSTEM FOR PESTICIDE DETECTION | Fundación AZTI - AZTI Fundazioa (ES) | 2024-06-05 | — | — | EP | disclosed |
| US-20240175069-A1 | BIOSYSTEM FOR PESTICIDE DETECTION | Fundación AZTI – AZTI Fundazioa (ES) | 2024-05-30 | — | — | US | disclosed |
| US-20240060949-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | FUNDACION AZTI/AZTI FUNDAZIOA (ES) | 2024-02-22 | — | — | US | disclosed |
| EP-4271830-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | Fundacion Azti/Azti Fundazioa (ES) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022144095-A1 | BIOSYSTEMS TO DETECT CHEMICAL CONTAMINANTS | FUNDACION AZTI/AZTI FUNDAZIOA (ES) | 2022-07-07 | — | — | WO | disclosed |
| CN-108368095-B | D-proline derivatives as SAP consumables | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-06-08 | — | — | CN | disclosed |
| EP-1238097-B9 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SMITHKLINE BEECHAM PLC (GB) | 2007-05-30 | — | — | EP | disclosed |
| EP-1238097-B9 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SMITHKLINE BEECHAM PLC (GB) | 2007-05-30 | — | — | EP | disclosed |
| EP-1238097-B1 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SMITHKLINE BEECHAM PLC (GB) | 2006-08-23 | — | — | EP | disclosed |
| EP-1238097-B1 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SMITHKLINE BEECHAM PLC (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-7056654-B2 | Screening assay for inhibitors of human cytochrome P-450 | SMITHKLINE BEECHAM CORPORATION (US) | 2006-06-06 | — | — | US | disclosed |
| US-20030077686-A1 | Enzyme substrate | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-04-24 | — | — | US | disclosed |
| EP-1238097-A2 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SmithKline Beecham plc (GB) | 2002-09-11 | — | — | EP | disclosed |
| EP-1238097-A2 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SmithKline Beecham plc (GB) | 2002-09-11 | — | — | EP | disclosed |
| US-6420131-B1 | MONITORING PREFRENTIAL ENZYMATIC ACTIVITY; OBTAIN SAMPLE OF ENZYMATIC POLYPEPTIDE, INCUBATE WITH MODULATOR, EVALUATE THE MODULATOR ABILITY TO INHIBIT ENZYMATIC POLYPEPTIDE | GENTEST CORPORATION | 2002-07-16 | — | — | US | disclosed |
| EP-1210342-A1 | THE USE OF FLUORESCEIN ARYL ETHERS IN HIGH THROUGHPUT CYTOCHROME P450 INHIBITION ASSAYS | GENTEST CORPORATION (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001044495-A3 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SMITHKLINE BEECHAM PLC (GB) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001044495-A2 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001044495-A2 | DIETHOXYFLUORESCEIN AS INDICATOR FOR CYTOCHROME P450 | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-06-21 | — | — | WO | disclosed |
| WO-2001014361-A1 | THE USE OF FLUORESCEIN ARYL ETHERS IN HIGH THROUGHPUT CYTOCHROME P450 INHIBITION ASSAYS | GENTEST CORPORATION (US) | 2001-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030077686-A1 | Enzyme substrate | CYP3A43, CYP2E1, POR | FTO 254/4885HPGD 220/4885MAPT 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.