Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135155 | 0.86 | ADORA3 (0.40) | ADORA3 | |
| SCHEMBL7873273 | 0.85 | ADORA3 (0.39) | ADORA3MEN1KMT2A | |
| SCHEMBL7873331 | 0.83 | MAPT (0.36) | ADORA3MEN1KMT2A | |
| SCHEMBL7864153 | 0.83 | ADORA3 (0.39) | ADORA3 | |
| SCHEMBL8138174 | 0.81 | ADORA3 (0.36) | ADORA3 | |
| SCHEMBL7864187 | 0.81 | ADORA3 (0.39) | ADORA3 | |
| SCHEMBL7876067 | 0.79 | ADORA3 (0.38) | ADORA3 | |
| SCHEMBL7876028 | 0.79 | ADORA3 (0.38) | ADORA3 | |
| SCHEMBL7869604 | 0.77 | ADORA3 (0.40) | ADORA3 | |
| SCHEMBL7864225 | 0.77 | ADORA3 (0.41) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306853-B1 | DICARBOXYLIC ESTER DERIVATIVES OF DIHYDROPYRIDINE COMPOUNDS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |