Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.36 |
| ▸ | RAB7A | P51149 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155949 | 0.86 | RAB7A (0.33) | ALDH1A1RAB7ATSHR | |
| SCHEMBL7846887 | 0.86 | ALDH1A1 (0.39) | ALDH1A1RAB7ATSHRHSD17B10KMT2A | |
| SCHEMBL7568404 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL5843765 | 0.84 | ALDH1A1 (0.38) | ALDH1A1RAB7ATSHRHSD17B10KMT2A | |
| SCHEMBL6315438 | 0.84 | PTPN1 (0.42) | RAB7A | |
| SCHEMBL7692364 | 0.84 | KMT2A (0.34) | ALDH1A1RAB7AKMT2AMEN1GAA | |
| SCHEMBL6225735 | 0.83 | ALDH1A1 (0.37) | ALDH1A1RAB7ATSHRCYP1A2CYP2C9 | |
| SCHEMBL7862333 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL7563366 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL7567316 | 0.82 | RAB7A (0.33) | ALDH1A1RAB7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080095-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999046267-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 1999-09-16 | — | — | WO | disclosed |