Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21683301 | 0.81 | LMNA (0.45) | F2LMNAF10MEN1KMT2A | |
| SCHEMBL21683300 | 0.81 | LMNA (0.45) | F2LMNAF10MEN1KMT2A | |
| SCHEMBL7337416 | 0.81 | PLAU (0.60) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL335254 | 0.80 | MEN1 (0.50) | LMNAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL15328453 | 0.80 | MEN1 (0.50) | LMNALOXL2MEN1KMT2AHTT | |
| SCHEMBL7337293 | 0.79 | PLAU (0.60) | PRSS1F2PLG | |
| SCHEMBL356816 | 0.78 | MEN1 (0.51) | LMNAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL7463434 | 0.78 | PRSS1 (0.58) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL18527956 | 0.78 | MEN1 (0.51) | LMNAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL8773482 | 0.77 | MEN1 (0.69) | LMNAMEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701568-B1 | NEW PEPTIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-25 | — | — | EP | disclosed |
| EP-1067136-A1 | New peptide derivatives | AstraZeneca AB (SE) | 2001-01-10 | — | — | EP | disclosed |