Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.58 |
| ▸ | ITGAV | P06756 | 12/20 | 0.58 |
| ▸ | EEF2K | O00418 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864311 | 1.00 | ITGB3 (0.58) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL7863260 | 0.87 | ITGB3 (0.47) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL7863178 | 0.87 | ITGB3 (0.47) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL5878214 | 0.81 | ITGB3 (0.77) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL5878211 | 0.81 | ITGB3 (0.77) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL7864316 | 0.80 | GBA1 (0.41) | ITGB3ITGAVL3MBTL1ALDH1A1 | |
| SCHEMBL5878018 | 0.80 | ITGB3 (0.77) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL5878024 | 0.80 | ITGB3 (0.77) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL6366667 | 0.80 | ITGB3 (0.60) | ITGB3ITGAVEEF2KATML3MBTL1 | |
| SCHEMBL6368255 | 0.78 | ITGB3 (0.58) | ITGB3ITGAVEEF2KATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889877-B1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | SEARLE & CO (US) | 2001-08-29 | — | — | EP | claimed |