Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | FNTA | P49354 | 3/20 | 0.32 |
| ▸ | FNTB | P49356 | 3/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864465 | 0.84 | FNTA (0.39) | PTGS2IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7564412 | 0.81 | FNTA (0.49) | PTGS2IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7561955 | 0.76 | FNTA (0.51) | PTGS2IDO1FNTAFNTBCYP3A4 | |
| SCHEMBL7612438 | 0.75 | FNTA (0.49) | PTGS2IDO1FNTAFNTB | |
| SCHEMBL7570972 | 0.75 | IDO1 (0.49) | PTGS2IDO1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7568488 | 0.73 | PTGS2 (0.40) | PTGS2IDO1FNTAFNTBPGGT1B | |
| SCHEMBL7562597 | 0.73 | FNTA (0.49) | PTGS2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7662191 | 0.72 | FNTA (0.38) | PTGS2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL8194789 | 0.72 | FNTA (0.39) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL8194792 | 0.70 | FNTA (0.40) | FNTAFNTBPGGT1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-09-05 | — | — | EP | claimed |