Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.40 |
| ▸ | FNTB | P49356 | 4/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864465 | 0.86 | FNTA (0.39) | FNTAFNTBPGGT1BRAB9AMAPT | |
| SCHEMBL7565357 | 0.85 | FNTA (0.44) | FNTAFNTBPGGT1BCYP24A1CYP19A1 | |
| SCHEMBL8194789 | 0.83 | FNTA (0.39) | FNTAFNTBPGGT1BRAB9AHTT | |
| SCHEMBL7562579 | 0.74 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL7864468 | 0.70 | PTGS2 (0.37) | FNTAFNTBPGGT1BMAPT | |
| SCHEMBL8189057 | 0.70 | FNTA (0.45) | FNTAFNTBPGGT1BCYP24A1 | |
| SCHEMBL7662187 | 0.69 | FNTA (0.52) | FNTAFNTBPGGT1BCYP26A1HTT | |
| SCHEMBL7564412 | 0.69 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL8199738 | 0.68 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL7657859 | 0.67 | FNTA (0.51) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-09 | — | — | EP | claimed |
| WO-1999020611-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-04-29 | — | — | WO | claimed |