Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27142358 | 0.76 | NPC1 (0.68) | NPC1 | |
| SCHEMBL31571567 | 0.76 | NPC1 (0.68) | NPC1 | |
| SCHEMBL27142430 | 0.76 | NPC1 (0.68) | NPC1 | |
| Hydrochloric Acid SCHEMBL31571557 | 0.75 | NPC1 (0.67) | NPC1 | |
| SCHEMBL7419386 | 0.74 | KIF11 (0.51) | KIF11PARP1RAB9AKMT2AMEN1 | |
| SCHEMBL4725998 | 0.73 | KIF11 (0.84) | KIF11PARP1RAB9AKMT2AMEN1 | |
| SCHEMBL29708168 | 0.73 | KIF11 (0.84) | KIF11PARP1RAB9AKMT2AMEN1 | |
| SCHEMBL7541380 | 0.70 | KIF11 (0.56) | KIF11PARP1RAB9AKMT2AMEN1 | |
| SCHEMBL31571579 | 0.70 | GPR84 (0.64) | NPC1 | |
| SCHEMBL27142512 | 0.70 | GPR84 (0.64) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801059-B1 | INDOLE DERIVATIVE | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-06-27 | — | — | EP | disclosed |