Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.62 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.60 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.58 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.52 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797392 | 1.00 | HRH3 (0.62) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2881922 | 0.80 | L3MBTL3 (0.74) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL13085892 | 0.80 | L3MBTL3 (0.74) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4765933 | 0.78 | L3MBTL3 (0.71) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2884997 | 0.78 | L3MBTL3 (0.71) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2879388 | 0.77 | HRH3 (0.69) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Hydrochloric Acid SCHEMBL2883905 | 0.77 | L3MBTL3 (0.69) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL2884059 | 0.77 | HRH3 (1.00) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL15154902 | 0.76 | GAA (0.57) | HRH3HDAC1HDAC6 | |
| SCHEMBL2884617 | 0.75 | HRH3 (1.00) | HRH3L3MBTL3L3MBTL1MBTD1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133544-A1 | PIPERAZINE AND AMINOPYRROLIDINE COMPOUNDS AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC AG (DE) | 2010-11-25 | — | — | WO | disclosed |