Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864560 | 1.00 | KDM4E (0.53) | KDM4EHSD17B10TSHRRECQLALDH1A1 | |
| SCHEMBL8741664 | 1.00 | KDM4E (0.53) | KDM4EHSD17B10TSHRRECQLALDH1A1 | |
| SCHEMBL7864562 | 1.00 | KDM4E (0.53) | KDM4EHSD17B10TSHRRECQLALDH1A1 | |
| SCHEMBL2543692 | 0.80 | HSD17B10 (0.51) | KDM4EHSD17B10TSHRRECQLALDH1A1 | |
| SCHEMBL1018224 | 0.77 | ALDH1A1 (0.51) | KDM4EHSD17B10TSHRRECQLALDH1A1 | |
| SCHEMBL7859310 | 0.74 | GRM6 (0.42) | KDM4EALDH1A1L3MBTL1MAPTCYP2C19 | |
| SCHEMBL7859306 | 0.74 | GRM6 (0.42) | KDM4EALDH1A1L3MBTL1MAPTCYP2C19 | |
| SCHEMBL7859308 | 0.74 | GRM6 (0.42) | KDM4EALDH1A1L3MBTL1MAPTCYP2C19 | |
| SCHEMBL9114959 | 0.71 | KDM4E (0.49) | KDM4EHSD17B10TSHRRECQLALDH1A1 | |
| SCHEMBL7311871 | 0.70 | SMN1; SMN2 (0.44) | ALDH1A1L3MBTL1CRBNNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937036-B1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER AG (US) | 2001-12-05 | — | — | EP | disclosed |