Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383824 | 0.87 | ALOX15 (0.47) | ALOX15HSD17B10HSD17B3BCL9CTNNB1 | |
| SCHEMBL13719980 | 0.85 | ALDH1A1 (0.51) | ALOX15NPC1USP2RAB9ASMN1; SMN2 | |
| SCHEMBL22444645 | 0.84 | ALOX15 (0.50) | ALOX15NPC1USP2RAB9ASMN1; SMN2 | |
| SCHEMBL28353394 | 0.83 | ALOX15 (0.56) | ALOX15NPC1USP2RAB9ASMN1; SMN2 | |
| SCHEMBL22435385 | 0.82 | ALOX15 (0.51) | ALOX15HSD17B10HSD17B3BCL9CTNNB1 | |
| SCHEMBL6793192 | 0.81 | ALOX15 (0.55) | ALOX15NPC1USP2RAB9ASMN1; SMN2 | |
| SCHEMBL11567759 | 0.80 | ALOX15 (0.49) | ALOX15HSD17B3BCL9CTNNB1HTT | |
| SCHEMBL6742916 | 0.79 | ALOX15 (0.52) | ALOX15NPC1USP2RAB9ASMN1; SMN2 | |
| SCHEMBL25414746 | 0.78 | ALOX15 (0.48) | ALOX15SMN1; SMN2HSD17B10HSD17B3BCL9 | |
| SCHEMBL1162157 | 0.78 | KDM4E (0.51) | ALOX15SMN1; SMN2HSD17B10BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300495-B1 | REACTING ORGANIC AMINE SALT OF CLAVULANIC ACID WITH METAL SALT IN LIQUID MEDIUM OF FLUORINATED AND/OR CHLORINATED HYDROCARBON | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-10-09 | — | — | US | disclosed |