Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888772 | 0.90 | TP53 (0.37) | TP53FDPSCA2FAAHDNM1 | |
| SCHEMBL3664636 | 0.81 | TP53 (0.43) | TP53GPR84FDPSFFAR1CA2 | |
| SCHEMBL18110402 | 0.79 | CA12 (0.34) | TP53FDPSCA2TSHR | |
| SCHEMBL14641579 | 0.79 | DNM1 (0.42) | TP53GPR84FDPSFFAR1CA2 | |
| SCHEMBL6363952 | 0.79 | CA2 (0.42) | TP53GPR84FDPSFFAR1CA2 | |
| SCHEMBL27420807 | 0.79 | TP53 (0.52) | TP53GPR84FDPSFFAR1CA2 | |
| SCHEMBL14642186 | 0.79 | TP53 (0.52) | TP53GPR84FDPSFFAR1CA2 | |
| SCHEMBL3627346 | 0.77 | TP53 (0.41) | TP53GPR84FDPSFFAR1CA2 | |
| SCHEMBL14627179 | 0.77 | TP53 (0.41) | TP53GPR84FDPSFFAR1CA2 | |
| SCHEMBL27796336 | 0.77 | MAPT (0.45) | TP53GPR84FDPSFFAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089749-A4 | NOVEL THERAPEUTIC AGENTS FOR MEMBRANE TRANSPORTERS | ADVANCED MEDICINE INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1089749-A1 | NOVEL THERAPEUTIC AGENTS FOR MEMBRANE TRANSPORTERS | Advanced Medicine, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999064045-A1 | NOVEL THERAPEUTIC AGENTS FOR MEMBRANE TRANSPORTERS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |