SCHEMBL7864909

SCHEMBL7864909

FC(F)(F)Sc1c[nH]c(SC(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTPN1 P18031 1/20 0.32
PTPRZ1 P23471 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7872376 0.62 KDM4E (0.39) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL10382746 0.60 KDM4E (0.33) KDM4EALDH1A1TDP1
SCHEMBL7603891 0.60 KDM4E (0.43) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL20411965 0.60 KDM4E (0.42) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL900510 0.59 KDM4E (0.41) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL16707569 0.59 ALDH1A1 (0.46) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL22028275 0.57 AHR (0.50) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL16707603 0.57 SMN1; SMN2 (0.42) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL777056 0.57 ALDH1A1 (0.56) KDM4EALDH1A1TDP1PTPN1PTPRZ1
SCHEMBL16707484 0.56 SMN1; SMN2 (0.41) KDM4EALDH1A1TDP1PTPN1PTPRZ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830709-B1 ELECTROLYTE MATERIALS CONTAINING HIGHLY DISSOCIATED METAL ION SALTS MOLTECH CORP (US) 2001-07-04 EP disclosed
EP-0830709-A4 ELECTROLYTE MATERIALS CONTAINING HIGHLY DISSOCIATED METAL ION SALTS MOLTECH CORP (US) 1998-05-20 EP disclosed
EP-0830709-A1 ELECTROLYTE MATERIALS CONTAINING HIGHLY DISSOCIATED METAL ION SALTS Moltech Corporation (US) 1998-03-25 EP disclosed
WO-1996029753-A9 ELECTROLYTE MATERIALS CONTAINING HIGHLY DISSOCIATED METAL ION SALTS 1997-01-16 WO disclosed
WO-1996029753-A1 ELECTROLYTE MATERIALS CONTAINING HIGHLY DISSOCIATED METAL ION SALTS MOLTECH CORPORATION (US) 1996-09-26 WO disclosed
US-5538812-A ELECTROLYTIC CELLS WITH POLYETHERSILOXANES WITH GROUPS OF TRIFLUOROMETHANESULFONYL MOLTECH CORPORATION (US) 1996-07-23 US disclosed