Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261939 | 0.71 | — | — | |
| SCHEMBL7804275 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL3260980 | 0.67 | — | — | |
| SCHEMBL777056 | 0.64 | ALDH1A1 (0.56) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL8943068 | 0.62 | MAOA (0.40) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11722257 | 0.62 | — | — | |
| SCHEMBL5620006 | 0.62 | ALDH1A1 (0.54) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL7940607 | 0.62 | ALDH1A1 (0.61) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL10978325 | 0.62 | ALDH1A1 (0.61) | KDM4EALDH1A1TDP1PTPRZ1PTPN1 | |
| SCHEMBL827436 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016124563-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHSAFT (DE) | 2016-08-11 | — | — | WO | disclosed |
| EP-0708090-B1 | Intermediates useful for the synthesis of pesticides | AVENTIS CROPSCIENCE SA (FR) | 2002-12-04 | — | — | EP | disclosed |
| US-6271392-B1 | Intermediates useful for the synthesis of 1-arylpyrrole pesticides | RHONE-POULENC INC. | 2001-08-07 | — | — | US | disclosed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | disclosed |