SCHEMBL7864933

SCHEMBL7864933

CCCCCCCCCCOc1cnc(-c2ccc(CCC(C)O)cc2)nc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 2/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 2/20 0.51
USP2 O75604 2/20 0.51
KMT2A Q03164 2/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
NPC1 O15118 4/20 0.47
RARB P10826 4/20 0.45
HRH3 Q9Y5N1 1/20 0.44
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
CASP1 P29466 1/20 0.40
SLCO1B3 Q9NPD5 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7862172 1.00 RAB9A (0.51) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL7865001 0.94 RAB9A (0.53) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL8565141 0.93 RAB9A (0.55) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL8045876 0.93 RAB9A (0.55) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL8591279 0.87 RAB9A (0.42) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL8620927 0.85 MAPT (0.40) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL8716741 0.85 HRH3 (0.55) SMN1; SMN2ALDH1A1MEN1USP2KMT2A
SCHEMBL7856791 0.85 RAB9A (0.52) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL9636365 0.85 RAB9A (0.68) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL9636329 0.85 RAB9A (0.68) RAB9ASMN1; SMN2KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2275864-A None JP disclosed
EP-1067122-A2 Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-10 EP disclosed
US-5539115-A FERROELECTRIC CRYSTALS FOR OPTICAL APPARATUS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-23 US disclosed
EP-0435632-A2 Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-07-03 EP disclosed
JP-H02275864-A OPTICALLY ACTIVE ALCOHOLS AND ITS PRODUCTION SUMITOMO CHEM CO LTD 1990-11-09 JP disclosed