SCHEMBL7865178

SCHEMBL7865178

CCC(C)Oc1ccc(-n2cc(C(=O)O)cn2)cc1C#N

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7860399 0.92 XDH (0.64) XDH
SCHEMBL5407935 0.91 XDH (0.68) XDH
SCHEMBL7862862 0.89 XDH (0.53) XDH
SCHEMBL5401312 0.86 XDH (0.70) XDH
SCHEMBL5401317 0.86 XDH (0.70) XDH
SCHEMBL5414808 0.84 XDH (0.71) XDH
SCHEMBL5419378 0.84 XDH (0.74) XDH
SCHEMBL27406521 0.83 XDH (0.69) XDH
SCHEMBL5412822 0.82 XDH (0.71) XDH
SCHEMBL5412922 0.82 XDH (0.74) XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0936217-B1 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF WELFIDE CORP (JP) 2001-11-07 EP disclosed
US-6015829-A 1-phenylpyrazole compounds and medicinal application thereof YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2000-01-18 US disclosed
EP-0936217-A1 1-PHENYLPYRAZOLE COMPOUNDS AND MEDICINAL APPLICATION THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1999-08-18 EP disclosed