Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.68 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18381240 | 1.00 | LTA4H (0.68) | LTA4HSLC15A1ATMMMEACE | |
| SCHEMBL5498835 | 0.91 | SLC15A1 (0.66) | LTA4HSLC15A1MMEACE | |
| SCHEMBL5498833 | 0.91 | SLC15A1 (0.66) | LTA4HSLC15A1MMEACE | |
| SCHEMBL11254327 | 0.91 | ALPI (0.59) | LTA4HSLC15A1 | |
| SCHEMBL9113781 | 0.91 | ALPI (0.59) | LTA4HSLC15A1 | |
| SCHEMBL18375234 | 0.91 | ALPI (0.59) | LTA4HSLC15A1 | |
| SCHEMBL16559587 | 0.89 | ALPI (0.58) | LTA4H | |
| Hydrochloric Acid SCHEMBL2927527 | 0.89 | ALPI (0.58) | LTA4HSLC15A1 | |
| SCHEMBL7877012 | 0.88 | SLC7A5 (0.55) | LTA4HSLC15A1 | |
| SCHEMBL21010316 | 0.87 | SLC15A1 (0.64) | LTA4HSLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668776-B1 | Memory enhancing substances | HOPE CITY (US) | 2000-04-12 | — | — | EP | claimed |
| US-5652334-A | TETRAPEPTIDES | CITY OF HOPE (US) | 1997-07-29 | — | — | US | claimed |
| CN-114478476-A | Tetrahydronaphthalenes compounds, pharmaceutical compositions and uses thereof | 广州市恒诺康医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-6320024-B1 | PEPTIDES ASSOCIATED WITH INTENSIFIED BRAIN ACTIVITY; FOR TREATMENT OF AGING, INFECTIONS, AND BRAIN INJURY | CITY OF HOPE | 2001-11-20 | — | — | US | disclosed |
| EP-0668776-B1 | Memory enhancing substances | HOPE CITY (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5652334-A | TETRAPEPTIDES | CITY OF HOPE (US) | 1997-07-29 | — | — | US | disclosed |