Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231747 | 0.92 | ALDH1A1 (0.52) | ALDH1A1PAMDGKACES2CES1 | |
| SCHEMBL16907299 | 0.90 | ALDH1A1 (0.56) | ALDH1A1PAMDGKACES2CES1 | |
| SCHEMBL28573654 | 0.86 | ALDH1A1 (0.46) | ALDH1A1PAMDGKACES2CES1 | |
| SCHEMBL23476396 | 0.85 | ALDH1A1 (0.41) | ALDH1A1PAMDGKACES2CES1 | |
| SCHEMBL29948119 | 0.85 | PAM (0.61) | ALDH1A1PAMDGKACES2CES1 | |
| SCHEMBL11459168 | 0.84 | ALDH1A1 (0.44) | ALDH1A1PAMDGKAMAPTMEN1 | |
| SCHEMBL10872223 | 0.84 | PAM (0.50) | ALDH1A1PAMDGKACES2CES1 | |
| SCHEMBL27516917 | 0.83 | PAM (0.59) | ALDH1A1PAMDGKAMAPTMEN1 | |
| SCHEMBL11471903 | 0.83 | GAA (0.54) | ALDH1A1PAMMAPTMEN1NPC1 | |
| SCHEMBL28847927 | 0.83 | PAM (0.63) | ALDH1A1PAMDGKACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| CN-103333084-B | 3,3'-azobis[6-(butanoyloxy)benzoic acid] and preparation method and application thereof | SHAANXI PHARMACEUTICAL DEV CT | 2015-01-07 | — | — | CN | disclosed |
| CN-103333084-A | 3,3'-azobis[6-(butanoyloxy)benzoic acid] and preparation method and application thereof | SHAANXI PHARMACEUTICAL DEV CT | 2013-10-02 | — | — | CN | disclosed |
| EP-1120397-A2 | Process for preparing triazole derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | disclosed |
| US-6046354-A | CHEMICAL INTERMEDIATES, E.G. 2-ARYL-1,3-DIACYLOXY-2-PROPANOL, FOR DRUGS AND FUNGICIDES,E.G. (R)-2-(2,4-DIFLUOROPHENYL)-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPANE-1,2-DIOL, | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-04-04 | — | — | US | disclosed |
| US-5840553-A | OPTICALLY ACTIVE 2-ARYL-3-ACYLOXY-1,2,-PROPANE DIOL USING A MICROORGANISM OR ENZYME DERIVED FROM PORCINE PANCREAS; VIA STEREOSPECIFIC HYDROLYSIS OF A 2-ARYL-1,3-DIACYLOXY-2-PROPANOL; SYNTHETIC CHEMICAL INTERMEDIATES, FUNGICIDES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5654472-A | OPTICALLY PURE 2-ARYL-3-ACYLOXY-1,2-PROPANEDIOL COMPOUNDS; CHEMICAL INTERMEDIATES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0704419-A1 | PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | CYP21A2, CYP46A1, CYP17A1 | ALDH1A1 1218/4885PAM 1959/4885DGKA 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.