Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195573 | 0.69 | EPHX1 (0.45) | GRIN2BOPRM1OPRL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19853699 | 0.69 | GRIN2B (0.54) | GRIN2BOPRM1OPRL1 | |
| SCHEMBL3742060 | 0.67 | MAPK1 (0.49) | GRIN2BMC4RALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28502622 | 0.67 | KDM1A (0.47) | GRIN2BKDM1AMAOA | |
| SCHEMBL23023073 | 0.65 | KDM1A (0.41) | GRIN2BOPRM1OPRL1KDM1AMAOA | |
| SCHEMBL31312678 | 0.65 | MC4R (0.43) | GRIN2BMC4RKDM1AMAOA | |
| SCHEMBL8186106 | 0.64 | GRIN2B (0.56) | GRIN2BMC4ROPRM1OPRL1KDM1A | |
| SCHEMBL15601254 | 0.64 | GRIN2B (0.41) | GRIN2BMC4ROPRM1OPRL1KDM1A | |
| SCHEMBL22144684 | 0.64 | ALKBH5 (0.44) | GRIN2BKDM1AMAOAHSD17B10ALDH1A1 | |
| SCHEMBL9690902 | 0.64 | ALKBH5 (0.44) | GRIN2BKDM1AMAOAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148047-A2 | Processes for preparing cyclic compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-6218548-B1 | (TRIARYLMETHYL)AMINOSPIROPYRROLES | DAIICHI PAHARMACEUTICAL CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0829473-A1 | PROCESSES FOR PREPARING CYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |