SCHEMBL7865565

SCHEMBL7865565

CCC(C)Nc1ccc(Cl)nc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
ALDH1A1 P00352 2/20 0.59
TP53 P04637 1/20 0.59
HSP90AA1 P07900 1/20 0.59
CYP3A4 P08684 1/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
CASP1 P29466 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HIF1A Q16665 1/20 0.59
HSD17B10 Q99714 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
HCAR3 P49019 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPT P10636 1/20 0.40
KCNQ3 O43525 5/20 0.39
KCNQ2 O43526 5/20 0.39
KCNE1 P15382 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9219043 0.81 KCNQ3 (0.37) L3MBTL1ALDH1A1TP53HSP90AA1CYP3A4
SCHEMBL3824428 0.81 KCNQ3 (0.42) L3MBTL1ALDH1A1CYP3A4THRBALOX15
SCHEMBL12697232 0.80 TP53 (0.61) L3MBTL1ALDH1A1TP53HSP90AA1CYP3A4
SCHEMBL21276075 0.79 ALDH1A1 (0.59) L3MBTL1ALDH1A1TP53HSP90AA1CYP3A4
SCHEMBL12695051 0.79 TP53 (0.59) L3MBTL1ALDH1A1TP53HSP90AA1CYP3A4
SCHEMBL17461800 0.79 ALDH1A1 (0.59) L3MBTL1ALDH1A1TP53HSP90AA1CYP3A4
SCHEMBL12695048 0.79 TP53 (0.59) L3MBTL1ALDH1A1TP53HSP90AA1CYP3A4
SCHEMBL9869934 0.78 KCNQ3 (0.36) L3MBTL1ALDH1A1MEN1KMT2AMAPT
SCHEMBL10584828 0.76 KCNQ3 (0.40) SMN1; SMN2KCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL49805 0.76 ALDH1A1 (1.00) L3MBTL1ALDH1A1TP53HSP90AA1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001253872-A DERIVATIVE OF 6-CHLORO-3-PYRIDYLMETHYLPROPYLAMINE, METHOD FOR PREPARATION OF THE SAME AND MICROBICIDE KUREHA CHEM IND CO LTD 2001-09-18 JP disclosed