Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 6/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865565 | 0.78 | L3MBTL1 (0.59) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL9219043 | 0.74 | KCNQ3 (0.37) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL3824428 | 0.73 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1ALDH1A1 | |
| SCHEMBL4442545 | 0.70 | ADRA2A (0.49) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL10851455 | 0.70 | TDP1 (0.46) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10584828 | 0.69 | KCNQ3 (0.40) | KCNQ3KCNQ2KCNE1KCNQ1TNF | |
| SCHEMBL9220618 | 0.67 | STK17A (0.44) | KCNQ3KCNQ2KCNE1KCNQ1ALDH1A1 | |
| SCHEMBL7662714 | 0.67 | RRM2 (0.44) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL7793613 | 0.67 | L3MBTL1 (0.45) | KCNQ3KCNQ2KCNE1KCNQ1MEN1 | |
| SCHEMBL1198471 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039686-A | Insecticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-08-13 | — | — | US | disclosed |