Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057957 | 0.86 | SLC6A3 (0.55) | HNF4AKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31636317 | 0.86 | SLC6A3 (0.55) | HNF4AKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27740045 | 0.86 | HNF4A (0.50) | HNF4AFOLH1BCAT2FABP3FABP4 | |
| SCHEMBL628030 | 0.86 | HNF4A (0.58) | HNF4AFOLH1BCAT2FABP3FABP4 | |
| SCHEMBL36146 | 0.85 | HNF4A (0.66) | HNF4AFOLH1BCAT2FABP3FABP4 | |
| SCHEMBL29376910 | 0.85 | HNF4A (0.66) | HNF4AFOLH1BCAT2FABP3FABP4 | |
| SCHEMBL29159124 | 0.85 | MAPT (0.54) | HNF4AFOLH1BCAT2FABP3FABP4 | |
| Bromide SCHEMBL8757513 | 0.83 | HNF4A (0.63) | HNF4AFOLH1BCAT2FABP3FABP4 | |
| SCHEMBL6661257 | 0.83 | HNF4A (0.63) | HNF4AFOLH1BCAT2FABP3FABP4 | |
| SCHEMBL2833055 | 0.83 | HNF4A (0.63) | HNF4AFOLH1BCAT2FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010023276-A1 | Polymeric material, method for its manufacture, and its utilization | PREFORM RAUMGLIEDERUNGSSYSTEME GMBH (DE) | 2001-09-20 | — | — | US | claimed |
| US-20010023276-A1 | Polymeric material, method for its manufacture, and its utilization | PREFORM RAUMGLIEDERUNGSSYSTEME GMBH (DE) | 2001-09-20 | — | — | US | disclosed |