Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18000546 | 0.76 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29614829 | 0.76 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3076524 | 0.76 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29966674 | 0.76 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29942654 | 0.76 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27724702 | 0.75 | BIRC5 (0.54) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL708998 | 0.73 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31393433 | 0.73 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3425584 | 0.72 | MAPT (0.47) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29478359 | 0.72 | PDE10A (0.52) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276802-B | Thiophene-quinoxaline unit containing fluorene copolymer as well as preparation method and application thereof | OCEANS KING LIGHTING TECH CO | 2013-09-04 | — | — | CN | disclosed |
| CN-102276802-A | Thiophene-quinoxaline unit containing fluorene copolymer as well as preparation method and application thereof | — | 2011-12-14 | — | — | CN | disclosed |
| CN-1343215-A | 6-O-substituted macrolides with antibacterial activity | ABBOTT LAB (US) | 2002-04-03 | — | — | CN | disclosed |
| EP-1161438-A1 | 6-O-SUBSTITUTED MACROLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055168-A1 | 6-O-SUBSTITUTED MACROLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 2000-09-21 | — | — | WO | disclosed |
| US-6054435-A | 6-O-substituted macrolides having antibacterial activity | ABBOTT LABORATORIES (US) | 2000-04-25 | — | — | US | disclosed |