SCHEMBL7865985

SCHEMBL7865985

CCCc1c(OC)cccc1C1=NC(C)(C)CO1

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ATM Q13315 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
ELANE P08246 1/20 0.35
HRH3 Q9Y5N1 2/20 0.34
ALOX5 P09917 1/20 0.33
PTGS2 P35354 1/20 0.33
CTSD P07339 1/20 0.32
HTR1A P08908 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22560182 0.93 KDM4E (0.43) KDM4EATMALDH1A1HTTELANE
SCHEMBL9364445 0.82 KDM4E (0.43) KDM4EATMALDH1A1HTTELANE
SCHEMBL29527964 0.81 KDM4E (0.50) KDM4EATMALDH1A1HTT
SCHEMBL540 0.81 KDM4E (0.50) KDM4EATMALDH1A1HTT
SCHEMBL9677104 0.81 KDM4E (0.46) KDM4EATMALDH1A1HTTELANE
SCHEMBL6299778 0.80 KDM4E (0.50) KDM4EALDH1A1
SCHEMBL9702416 0.80 KDM4E (0.50) KDM4EATMALDH1A1HTTHRH3
SCHEMBL7865982 0.79 KDM4E (0.42) KDM4EATMALDH1A1HTTHRH3
SCHEMBL6300208 0.79 KDM4E (0.39) KDM4EATMALDH1A1HTTHRH3
SCHEMBL10737493 0.78 KDM4E (0.47) KDM4EATMALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303814-B1 N-[1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC 2001-10-16 US disclosed
EP-0877745-B1 N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2001-07-25 EP disclosed
US-6130335-A N-([1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-10-10 US disclosed
US-6005108-A POST-EMERGENCE TOTAL VEGETATION CONTROL OR SELECTIVE CONTROL OF WEEDS IN WHEAT, RICE AND OIL-SEED RAPE CROPS JOHNSON TIMOTHY C (US) 1999-12-21 US disclosed
US-5965490-A NOVEL COMPOUNDS WITH IMPROVED SELECTIVITY TO VALUABLE CROPS AND IMPROVED TOXICOLOGICAL AND ENVIRONMENTAL ATTRIBUTES; APPLYING TO CONTROL WEEDS BY EITHER PREEMERGENCE OR POSTEMERGENCE APPLICATION DOW AGROSCIENCES LLC (US) 1999-10-12 US disclosed
US-5858924-A N-( 1, 2, 4! triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 1999-01-12 US disclosed