SCHEMBL7866022

SCHEMBL7866022

O=C1CCCCC1Cc1ccc(O)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.58
ESR2 Q92731 7/20 0.58
PTGS2 P35354 7/20 0.56
PTGS1 P23219 6/20 0.56
OPRK1 P41145 1/20 0.56
HTT P42858 1/20 0.56
KMT2A Q03164 1/20 0.56
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA4 P22748 2/20 0.51
CA6 P23280 2/20 0.51
CYP26A1 O43174 1/20 0.51
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11794580 0.98 ESR1 (0.56) ESR1ESR2PTGS2PTGS1OPRK1
SCHEMBL4595 0.84 PTGS2 (0.57) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL29169546 0.84 PTGS2 (0.57) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL9790769 0.84 PTGS2 (0.57) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL7623394 0.82 NPC1 (0.57) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL9147334 0.82 PTGS1 (0.52) ESR1ESR2PTGS2PTGS1OPRK1
SCHEMBL6387863 0.82 PTGS1 (0.52) ESR1ESR2PTGS2PTGS1OPRK1
SCHEMBL225031 0.82 PTGS2 (0.56) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL5517558 0.82 PTGS2 (0.52) PTGS2PTGS1OPRK1HTTKMT2A
SCHEMBL29169532 0.82 NPC1 (0.57) PTGS2PTGS1OPRK1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313351-B1 Process for producing alicyclic monoketones and process for producing alicyclic diketones HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-11-06 US disclosed