Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30927966 | 1.00 | TSHR (0.48) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL11846636 | 0.94 | CYP2C9 (0.47) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL10426254 | 0.89 | MMP13 (0.50) | NPC1MAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5172480 | 0.82 | ESR1 (0.52) | TSHRALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL284962 | 0.82 | ESR1 (0.52) | TSHRALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL637766 | 0.82 | ESR1 (0.52) | TSHRALDH1A1LMNACYP2D6CYP2C9 | |
| SCHEMBL21557850 | 0.81 | MAPT (0.52) | MAPTALDH1A1HDAC1HDAC6CYP2D6 | |
| SCHEMBL4326795 | 0.81 | MAPT (0.52) | MAPTALDH1A1HDAC1HDAC6CYP2D6 | |
| SCHEMBL197251 | 0.81 | MAPT (0.52) | MAPTALDH1A1HDAC1HDAC6CYP2D6 | |
| SCHEMBL198241 | 0.81 | MAPT (0.52) | MAPTALDH1A1HDAC1HDAC6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924156-A | Synthesis method of aza-aryl alcohol compound and chiral alpha-hydroxycarboxylic acid | 赣南师范大学 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023116774-A1 | COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE | 赛诺哈勃药业（成都）有限公司 | 2023-06-29 | — | — | WO | disclosed |
| US-6300499-B1 | α1-adrenergic receptor antagonists | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-09 | — | — | US | disclosed |
| US-4922010-A | Processes for preparing 2-substituted propionic acid and derivatives thereof | UBE INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |